Conan

“To all the people watching, I can never ever thank you enough for your kindness to me and I’ll think about it for the rest of my life. All I ask of you is one thing: please don’t be cynical. I hate cynicism. For the record, it’s my least favorite quality, and it doesn’t lead anywhere. Nobody in life gets exactly what they thought they would get, but if you work hard and you’re kind, I’m telling you, amazing things will happen.”

-Conan O’Brien

When he says this.  Especially when his voice quivers during that first sentence.  It kills me.

Go watch the last episode here or just skip to about 31 minutes in to see the entire final sign-off.